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Publication of a JA2 methodological guideline – Internal validity of non-randomised studies (NRS) on interventions

During Joint Action 1 a methodological guideline on internal validity of randomised studies (RCT) had been elaborated. It was recommended from different sides that EUnetHTA should also produce and consent a guidance document for the assessment of non-randomised studies. The new guideline has been developed by WP 7 to address this need. It contains a short critical review of existing tools for the assessment of the most relevant types of bias in interventional non-randomised studies.

2015-07-06_Internal validity of NRS_reply_Reply_to_Public Comments_final
Internal validity of non-randomised studies (NRS) on interventions_Guideline_Final Jul 2015_0