National uptake is the general implementation of any EUnetHTA output in a national context and may include the usage and implementation of the EUnetHTA tools and Joint Assessments.

The overview of national adaptation of EUnetHTA JA2 joint assessments, is available below.

What is national uptake?

"National uptake" is the general implementation of any EUnetHTA output (i.e. joint assessments, submission templates, guidelines, POP Database, HTA Core Model®, etc.) in a local (national/regional) setting.

Instances of national uptake by using for example the EUnetHTA tools:

  • A local HTA report produced de-novo with the use of the HTA Core Model®
  • A local HTA report produced with application of the EUnetHTA Adaptation Toolkit adapting one of the national/regional reports from a different country to local settings
  • A local HTA report produced as the outcome of a collaboration facilitated by the EUnetHTA POP Database
  • A local HTA report produced with application of or reference to one or more of the EUnetHTA Guidelines
  • A local HTA report clearly describing the development process that includes usage of or reference to any of these EUnetHTA tools

What is national adaptation?

"National adaptation" is a specific type of national uptake, i.e. the use of the EUnetHTA joint assessment results in national/regional setting. The purpose of national adaptation is to avoid duplication, to promote good practices in HTA processes and to effectively use time and financial resources.

A local HTA report can be produced by using full Core HTAs or Rapid HTAs produced in JA1 or JA2, where either the whole Core HTA/rapid HTA or parts of the Core HTA/rapid HTA is used. This can be done by:

  • Summarising: The translation of a joint assessment summary used for background information in a local report
  • Updating searches: The application of the original joint assessment search strategy to identify further recent evidence or extending/adding to the local search strategy
  • Adapting: The systematic extraction of relevant HTA information from an existing joint assessment/Core HTA (partly or fully)
  • Adopting: The use of a joint assessment without making any changes at all in its content (except a potential translation into the national language).

The minimum requirement for a national adaptation is inclusion of a explicit reference to the EUnetHTA joint assessment on which the local report was based.

The information on National Uptake and Adaptation, listed below, is based on the results from the two surveys on National Uptake conducted among all EUnetHTA Partners in April and September 2015, and on information shared by EUnetHTA Partners with the EUnetHTA Secretariat on an ongoing basis.

This list will be updated quarterly from now on. Latest update: 21 March, 2016.

The Spanish HTA Network developed the adapted national guidelines for Relative Effectiveness Assessment reports (“Guía para la elaboración de informes rápidos de evaluación de tecnologías sanitarias”), based on the EUnetHTA guidelines for REA. 

Title of EUnetHTA Output used for national adaptationCountry AgencyStatusLink to published reportDetails on adaptation processContact information
Core HTA on Abdominal aortic aneurysm (AAA)AustriaHVBPublished 2013

Link to report

In English

In this study, a previously defined screening strategy (as proposed by EUnetHTA) was tested and evaluated. The model itself allows answering additional questions, for example "Which is the optimal screening strategy?" Such a question can be investigated considering various outcome measurements (e.g. ruptures, death cases, ICER).

 

Dr. Gottfried Endel
Gottfried.endel@hvb.sozvers.at

and

Ingrid Wilbacher, Senior Researcher, PhD Ingrid.wilbacher@hvb.sozvers.at

CroatiaAAZPublished December 2013

Link to report

In Croatian

The information from the original EUnetHTA Core HTA was adapted and the text used for the national report on the same health problem; Abdominal Aortic Aneurism.

 

Mirjana Huic, MD, PhD
mirjana.huic@aaz.hr

NorwayNOKCPublished March 2014

Link to report

In English

The information from the original EUnetHTA Core HTA was adapted and transferred into the NOKC template for HTA reports.

Katrine Bjørnebek Frønsdal, Senior Researcher
kbf@nokc.no

Core HTA on Fecal Immunochemical Test (FIT) versus guaiac-based fecal occult blood test (FOBT) for colorectal cancer screeningAustriaBIQG/GÖG

and HVB

Published December 2014

Link to report

In German

The national report was produced on the EUnetHTA report. We summarized and translated essential components of Core-HTA. Furthermore we supplemented the report with national data and information and adapted it to he national setting.

 

Anna Renner
anna.renner@goeg.at

Ingrid Wilbacher, Senior Researcher, PhD Ingrid.wilbacher@hvb.sozvers.at

AustriaHVBPublished August 2015

Link to report

In German

 

Data extraction of EUnetHTA Core-Assessment and of a local report published by GÖG. In addition, a systematic literature search using the EUnetHTA search strategy was performed for studies about M2-PK stool test.

 

Dr. Gottfried Endel Gottfried.endel@hvb.sozves.at

and

Ingrid Wilbacher, Senior Researcher, PhD Ingrid.wilbacher@hvb.sovers.at

RomaniaNSPH MPDPublished 2015

Link to report

In Romanian with summary in English

The transferable parts of the Joint Assessment were translated in the national language and used for the local HTA report. Available national data were added to certain domains.

Silvia Gabriela Scintee

sgscintee@snspms.ro

Marius Ciutan

mciutan@snspms.ro

SloveniaIER and NIPH SloveniaPublished 2015

Link to report

Link to report

In Slovenian

National Adaptation

Valentina Prevolnik Rupel
rupelv@ier.si

Taja Čokl
taja.cokl@nijz.si

EstoniaUTA

Information missing.
For further details, please contact Ingrid Wilbacher: ingrid.wilbacher@hvb.zoverz.at

(WP3 LP) or Raul Kiivet: raul.kiivet@ut.ee

Raul Kiivet
raul.kiivet@ut.ee

SpainISC IIIUsed in direct decision-making.

Iñaki Imaz
imaz@isciii.es

SpainISC III

Used in cross-checking evidence.

Antonio Sarrria-Santamera
asarria@isciii.es

SwitzerlandSNHTA

Used in cross-checking evidence.

Christoph Künzli
christoph.kuenzli@bag.admin.ch

Pilot rapid assessment on Balloon Eustachian Tuboplasty for the treatment of Eustachian tube dysfunction

AustriaLBI-HTAPublished 2015

Link to report

In German

The EUnetHTA assessment has been translated into German; in addition, the literature search has been updated and some recent evidence included. National data on e.g. burden of disease/cost were added whenever available.

Julia Mayer
Julia.mayer@hta.lbg.ac.at

FinlandTHLPublished 2015

Link to report

In Finnish

The EUnetHTA assessment was directly translated into finnish and further information on a survey conducted for ear-nose-throat-doctors was added.

Kristian Lampe
kristian.lampe@thl.fi

SpainAETSAPublished 2015

Link to report

In Spanish

The EUnetHTA reports was adopted, i.e. use of a joint assessment without making any changes at all in its content.

Teresa Molina Lopez
mariat.molina.lopez@juntadeandalucia.es

AustriaHVB

 

Used in direct decision-making.

Gottfried Endel
gottfried.endel@hvb.sozvers.at

SlovakiaMoH SK

 

Used in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

Pilot rapid assessment on Biodegradable Stents for the treatment of refractory or recurrent benign oesophageal stenosis.AustriaLBI-HTAPublished 2015

Link to report

In German

The EUnetHTA assessment was translated into German; tables were directly used from the EUnetHTA assessment. National data on e.g. burden of disease/cost were added whenever available.

Claudia Wild
claudia.wild@hta.lbg.ac.at

AustriaLBI-HTA

Used in direct decision-making.

Claudia Wild
claudia.wild@hta.lbg.ac.at

AustriaLBI-HTA

Used in cross-checking evidence.

Claudia Wild
claudia.wild@hta.lbg.ac.at

AustriaHVB

 

Used in direct decision-making.

Gottfried Endel
gottfried.endel@hvb.sozvers.at

The NetherlandsZIN

Information missing.
For further details, please contact Ingrid Wilbacher:
ingrid.wilbacher@hvb.zoverz.at  
(WP3 LP) or Hedi Schelleman hschelleman@zinl.nl

Hedi Schelleman, Implementation Officer hschelleman@zinl.nl

SlovakiaMoH SK

 

Used in cross-checking evidence.

Tomas Tesar
tomas.tesar@union.sk

SpainAETSA

 

Used in direct decision-making.

Teresa Molina Lopez
mariat.molina.lopez@juntadeandalucia.es

Pilot rapid assessment on ‘Canagliflozin for the treatment of type 2 diabetes mellitus’
The NetherlandsZINPublished March 2014

Link to report

In Dutch

The results of the indirect analyses in the EUnetHTA report were mentioned in the discussion section of the favourable effects.

Hedi Schelleman, Implementation Officer
hschelleman@zinl.nl

SpainAETSAPublished July 2015

Link to report

In Spanish

The EUnetHTA assessment was adopted, i.e. systematic extraction of relevant HTA information from an existing joint assessment.

Teresa Molina Lopez
mariat.molina.lopez@juntadeandalucia.es

SpainMSSSIPublished June 2015

Link to report

In Spannish 

National Adaptation

Celia Juarez Rojo
cjuarex@msssi.es

ItalyAIFA

Information missing.
For further details, please contact Ingrid Wilbacher: ingrid.wilbacher@hvb.zoverz.at
(WP3 LP) or Agnese Cangini
a.cangini@aifa.gov.it

Agnese Cangini
a.cangini@aifa.gov.it

LuxembourgCMSS

 

Used in cross-checking evidence.

Yves Bruch
yves.bruch@secu.lu

MaltaMEH

 

Used in direct decision-making.

Antonia Formosa
antonia.formosa@gov.mt

PortugalINFARMED

 

Used in cross-checking evidence.

João Martins
joao.martins@infarmed.pt

SlovakiaMoH SK

 

Used in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

SpainAETSA

Used in cross-checking evidence.

Teresa Molina Lopez
mariat.molina.lopez@juntadeandalucia.es

SwedenTLV

Used in cross-checking evidence.

Johan Ponten
johan.ponten@tlv.se

Pilot rapid assessment on ‘Duodenal-jejunal bypass sleeve for the treatment of obesity with or without Type II Diabetes Mellitus'AustriaLBI-HTA and HVBPublished July 2013

Link to report

In German

An LBI report was produced alongside the EUnetHTA assessment. Due to time restrictions the LBI report had to be finished before it was possible to publish the EUnetHTA report. However, after the EUnetHTA assessment had been completed, the information provided therein was used to update the LBI report.

Dr. Ingrid Zechmeister-Koss, MA Ingrid.Zechmeister@hta.lbg.ac.at

Stefan Fischer
stefan.fischer@hta.lbg.ac.at

The NetherlandsZINPublished July 2015

Link to report

In Dutch

Parts of the Joint Assessment were translated in the national language and used for the local HTA report

Hedi Schelleman, Implementation Officer
hschelleman@zinl.nl

SpainISC IIIPublished September 2014

Link to report

In Spanish

The National HTA report of the Duodenal-jejunal bypass sleeve updated the Joint Assessment with the new evidence availble since the publication of the Joint Assessment.

Iñaki Imaz
imaz@isciii.es

AustriaHVB

 

Used in direct decision-making.

Gottfried Endel
gottfried.endel@hvb.sozvers.at

SlovakiaMoH SK

Used in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

Pilot rapid assessment on Ramucirumab in combination with Paclitaxel as second-line treatment for adult patients with advanced gastric or gastro-oesophageal junction adenocarcinomaAustriaLBI-HTAPublished September 2015

Link to report

In English

Adapting: systematic extraction of relevant HTA information from an existing joint assessment.

Anna Nachtnebel
anna.nachtnebel@hta.lbg.ac.at

BelgiumKCE

Published October 2015

Link to report

In English

Preparation of a 2 pages news-item.

Patrice Chalon
patrice.chalon@kce.fgov.be

FinlandFIMEAPublished 2015

Link to report

Abstract in English Report in Finnish

Adapting: systematic extraction of relevant HTA information from an existing joint assessment.

Ulla Harkonen
ulla.harkonen@fimea.fi

or

vesa.kiviniemi@fimea.fi

BelgiumRIZIV

 

Used in cross-checking evidence.

Francis Arickx
francis.arickx@riziv.fgov.be

FinlandFIMEA

 

Used in cross-checking evidence.

Pertti Happonen
pertti.happonen@fimea.fi

SlovakiaMoH SK

 

Used in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

BelgiumKCE

Link to summary

Analysis of scientific context and its relevance, "KCE has read for you". 

Patrice Chalon
patrice.chalon@kce.fgov.be

Pilot rapid assessment on Renal denervation systems for treatment-resistant hypertensionAustriaHVB

 

Used in direct decision-making.

Gottfried Endel
gottfried.endel@hvb.sozvers.at

ItalyASSR

Information missing.
For further details, please contact Ingrid Wilbacher: ing
rid.wilbacher@hvb.zoverz.at
(WP3 LP) or Luciana Ballini
luballini@regione.emilia-romagna.it

Luciana Ballini
luballini@regione.emilia-romagna.it

SlovakiaMoH SK

 

Used in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

SpainAVALIA-t

 

Used in direct decision-making.

Leonor Varela
leonor.varela.lema@sergas.es

SpainAVALIA-t

 

Used in cross-checking evidence.

Leonor Varela
leonor.varela.lema@sergas.es

SpainIASC

 

Used in direct decision-making.

Almudena Albertos
aalbertos@isciii.es

SpainOsteba

 

Used in cross-checking evidence.

Jose Asua
jasua@euskadi.eus

United KingdomHIS

 

Used in cross-checking evidence.

Jan Jones

janjones@nhs.net

Sorafenib for the treatment of advanced or metastatic progressive differentiated thyroid cancerUnited Kingdom
(Scotland)
HISPublished July 2015

Link to report

The EUnetHTA report was referenced in discussion on impact of sorafenib on health related quality of life.

Jan Jones
janjones@nhs.net

BelgiumRIZIV

Used in cross-checking evidence.

Francis Arickx
francis.arickx@riziv.fgov.be

PortugalINFARMED

 

Used in direct decision-making.

João Martins
joao.martins@infarmed.pt

SlovakiaMoH SKUsed in direct decision-making.

Tomas Tesar
tomas.tesar@union.sk

SpainIACS

Used in direct decision-making.

Almudena Albertos
aalbertos@isciii.es

BelgiumKCELink to summaryAnalysis of scientific context and its relevance, "KCE has read for you".

Patrice Chalon
patrice.chalon@kce.fgov.be

Pilot rapid assessment of Transcatheter implantable devices for mitral valve repair in adults with chronic mitral valve regurgitationAustriaLBI-HTAPublished 2015

Link to report

In German

The EUnetHTA assessment has been translated into German; in addition, the literature search has been updated and some recent evidence included. National data on e-g- burden of disease/cost were added whenever available.

Dr. Claudia Wild
Claudia.wild@hta.lbg.ac.at

AustriaHVB

Used in direct decision-making.

Gottfried Endel gottfried.endel@hvb.sozvers.at

Pilot of rapid assessment on ‘Zostavax for the prevention herpes zoster'AustriaLBI-HTA and HVBPublished November 2014

Link to report

In German

The EUnetHTA assessment was translated into German; tables were directly used from the EUnetHTA assessment.

Dr. Ingrid Zechmeister-Koss, MA
Ingrid.Zechmeister@hta.lbg.ac.at

AustriaLBI-HTAPublished November 2014

Link to report

In German

The EUnetHTA assessment was translated into German; tables were directly used from the EUnetHTA assessment. National data on e.g. burden of disease/cost were added whenever available.

 

Anna Nachtnebel
anna.nachtnebel@hta.lbg.ac.at

The NetherlandsZINPublished march 2014

Link to report

In Dutch

The results of the indirect analyses in the EUnetHTA report were mentioned in the discussion section of the favourable effects.

Hedi Schelleman, Implementation Officer
hschelleman@zinl.nl

AustriaHVBUsed in direct decision-making.

Gottfried Endel
gottfried.endel@hvb.sozvers.at

BelgiumRIZIVUsed in cross-checking evidence.

Francis Arickx
francis.arickx@riziv.fgov.be

SwedenTLVUsed in cross-checking evidence.

Johan Ponten
johan.ponten@tlv.se

Endovascular therapy using mechanical thrombectomy devices for acute ischaemic stroke

AustriaLBI-HTAPublished March 2016Link to reportGerman Summary of the correspondent EUnetHTA Report

Claudia Wild
Claudia.Wild@hta.lbg.ac.at

FranceHASPublished February 2017

Link to report

in French

Is partially based on the JA2 EUnetHTA Joint Assessment

 

Huguette Lhuillier-Nkandjeu h.lhuIlliernkandjeu@has-sante.fr

IrelandHIQAPublished February 2017Link to reportThis report, which references EUnetHTA, represents an update and adaptation of the REA undertaken as part of JA2.